Journal of Diverse Medical Research : Medicosphere

Indexed, Ranked, but Not Verified: Why Bibliometric Status Cannot Guarantee Scholarly Integrity in the Age of AI-Hallucinated Citations?

Ilham Kurniawan — 2026-05-29

Preamble

A question that should unsettle every editor, reviewer, and author is this: What happens when fabricated, unverifiable references appear in peer‑reviewed articles published in indexed journals? This is no longer hypothetical. It is a reality that forces us to confront an uncomfortable truth indexation is not innocence, and a Scopus badge is not a certificate of integrity. As Deputy Editor-in-Chief of Medicosphere, I believe this demands urgent attention. The integrity of the scholarly record the foundation of scientific progress is under threat from generative artificial intelligence.

Education on Ari Risk Mitigation Caused by Environmental Mold and Waste Management in The Community of Tembok Dukuh Sub-District, Bubutan District, Surabaya

Queency Felicia — 2026-05-29

Background: Acute Respiratory Infection (ARI) is the disease with the highest number of cases in Indonesia, with one of the often-overlooked environmental risk factors being mold growth caused by indoor humidity and poor waste management. Objective: This community service activity aimed to improve public knowledge and awareness regarding the relationship between environmental mold, waste management, and the risk of ARI, as well as to encourage the implementation of clean and healthy living behavior (PHBS). Methods: The activity was conducted on Saturday, 23 April 2026, from 07:45 to 10:00 WIB at Tembok Dukuh X Balai RT 12 RW 01, Tembok Dukuh Sub-district, Bubutan District, Surabaya, targeting 25 residents. The implementation method consisted of a pretest, education and outreach, interactive discussion, a waste management demonstration, and a posttest as the evaluation instrument using an 8-item multiple-choice questionnaire. Results: The results showed an increase in the participants’ average knowledge score from 6.88 (median 7; range 4–8) at pretest to 7.69 (median 8; range 7–8) at posttest, accompanied by a narrowing score range indicating more even understanding among participants. Conclusion: This activity proved effective in improving community knowledge regarding ARI risk mitigation due to environmental mold and waste management, and is expected to be applied sustainably in daily life.

Exploring the Antibacterial Potential of Xanthorrhizol from Curcuma xanthorrhiza Through Molecular Docking Technology

Raihan Rezky Fahrezy — 2026-05-29

The escalating threat of antimicrobial resistance (AMR) has emerged as a pressing global health challenge, with Gram-negative organisms most notably Escherichia coli bearing substantial responsibility for its clinical impact. This review critically assesses the feasibility of targeting UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) as an antibacterial drug target and the pharmacological potential of xanthorrhizol. The latter compound represents the predominant bioactive constituent isolated from the rhizome of Curcuma xanthorrhiza, a plant with established medicinal application. This review describes the robust antimicrobial spectrum of xanthorrhizol and defines the structural arrangements of the MurB enzyme that allow its pharmacological inhibition, through a thorough and exhaustive assessment of published literature. Central to our findings is the observation that MurB occupies an indispensable position within the peptidoglycan assembly pathway of bacteria, a function for which no mammalian counterpart exists an attribute that underscores its exceptional suitability as a selective therapeutic target, providing for a highly selective targeting mechanism with little risk of toxicity to the host. Xanthorrhizol also showed potent bactericidal activity against Gram-negative bacteria by successfully attacking their cellular defenses, preventing biofilm formation, and significantly reducing the count of viable cells. Therefore, xanthorrhizol looks like a very rational candidate for the development of new drugs. In conclusion, xanthorrhizol as an inhibitor of the MurB enzyme is a promising novel strategy in the fight against resistant E. coli infections and provides a good theoretical basis that needs further molecular docking simulations and in vitro validation.

Hazard Analysis and Critical Control Points (HACCP) as a Food Safety System Recommendation Compared to Conventional Sanitation in the Free Nutritious Meal Program (MBG) A Literature Review

Diyanty Nur Hidayah Putry Putry — 2026-05-29

Background: Food safety is a critical concern in structured nutrition programmes, such as Indonesia's Free Nutritious Meal Programme (MBG). Traditional hygiene practices alone may not effectively prevent food contamination, and the Hazard Analysis and Critical Control Points (HACCP) framework has been proposed as a more thorough, proactive alternative. Objective: This review compared HACCP with conventional sanitation practices and assessed its potential as a formal food safety framework for MBG.Methods: PubMed and ScienceDirect for articles published between 2020 and 2026 were searched using the PICO framework for open-access, English-language studies on HACCP and food safety in institutional catering published within the past decade. Following PRISMA-guided screening, 11 studies met all eligibility criteria and were included. Results: Included studies consistently found weaknesses in sanitation practices, food handlers' knowledge and behaviour, temperature control, and microbial contamination under conventional systems, while HACCP adoption improved hazard identification, compliance, hygiene monitoring, and microbial control.Conclusion: HACCP offers a more thorough, proactive approach than conventional sanitation alone and is recommended as MBG's core food-safety framework to reduce contamination risk and support the programme's long-term sustainability

Beyond the Patient: Family-Level Consequences of Cancer on Quality of Life, Productivity, and Economic Stability

Fitrotul Ainiyyah — 2026-05-29

Background: Cancer imposes a substantial global health burden, with consequences extending beyond the individual patient to affect family members who serve as primary caregivers throughout the disease trajectory. Despite growing recognition of caregiver burden, the multidimensional impacts on family quality of life, productivity, and economic stability remain insufficiently addressed in clinical practice and health policy. Objective: This narrative review aims to synthesize current evidence on the impact of cancer on family caregivers, particularly regarding quality of life, psychological well-being, work productivity, and financial stability. Methods: A literature search was conducted using PubMed, ScienceDirect, Springer Nature, Oxford Academic, and Google Scholar for articles published between 2020 and 2026 in English or Indonesian. A combination of Boolean operators (AND, OR) was applied with keywords including cancer, family, caregiver, quality of life, productivity, and financial toxicity. Following title, abstract, and full-text screening, 24 studies met the inclusion criteria and were analyzed using a comparative-critical synthesis approach. Results: The synthesis revealed that caregiving burden is a major determinant of reduced family quality of life, particularly in physical, emotional, and social domains. Psychological distress including anxiety, depression, and fatigue served as a significant mediator between caregiving burden and reduced well-being. Financial toxicity resulting from treatment costs and loss of work productivity further exacerbated these effects, especially in low- and middle-income countries. Conversely, protective factors including family resilience, perceived social support, and high-quality interpersonal relationships were consistently associated with lower perceived burden and better quality of life. Conclusion: Cancer caregiving generates cascading consequences on family well-being, mediated by psychological distress and economic strain. A family-centered care approach that integrates routine caregiver screening, psychosocial support, resilience-building interventions, and financial protection policies is urgently needed to improve outcomes for both patients and their families.

Optimizing Hazard Analysis and Critical Control Points (HACCP) Implementation in School Feeding Programs to Enhance Food Safety in LMICs: A Literature Review

Kayla Ardina Syaharani S — 2026-05-29

Background: School feeding programmes are among the largest nutrition and social protection interventions in low- and middle-income countries (LMICs). However, foodborne hazards remain a major challenge that may compromise programme effectiveness. As Indonesia expands its Makan Bergizi Gratis (MBG) programme, optimizing Hazard Analysis and Critical Control Point (HACCP) implementation is essential to ensure food safety. Objective: This literature review aimed to synthesize current evidence on HACCP implementation in school feeding programmes and identify evidence-based strategies to optimize food safety in LMICs, with implications for Indonesia’s MBG programme. Methods: A literature review was conducted through a systematic search of the PubMed and Europe PMC databases for studies published between 2016 and 2026. The search strategy was developed using the Population, Intervention, Comparison, and Outcome (PICO) framework, and study selection followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Six eligible primary studies were synthesized narratively, while international guidelines and Indonesian policy documents were reviewed to contextualize the findings. Results: Three major themes were identified: behavioural factors, microbiological contamination, and institutional capacity. The evidence demonstrated that conventional food safety measures were insufficient to ensure consistent food safety performance. Optimizing HACCP implementation required strengthening prerequisite programmes, workforce competency, continuous monitoring, systematic verification, integrated governance, and implementation fidelity. Conclusion: HACCP provides a comprehensive framework for improving food safety in school feeding programmes. The findings support strengthening implementation fidelity, institutional capacity, and multisectoral collaboration to ensure the safe and sustainable implementation of Indonesia’s MBG programme.